TOP LATEST FIVE KETAMINE ANTIDOTE MEDSCAPE URBAN NEWS

Metabolism Ketamine is metabolized via N-dealkylation on the active metabolite norketamine principally by CYP2B6 and CYP3A4 also to a lesser extent by other CYP enzymes. Norketamine undergoes hydroxylation with the cyclohexone ring to variety hydroxynorketamine compounds via CYP-dependent pathways, which are conjugated with glucuronic acid and subs